Research
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Proteomics identifies immunological drivers of post‐infection brain atrophy and cognitive decline
Abstract
Prior infections can modify the risk for dementia and neurodegenerative disease, yet the mechanisms by which infections contribute to neurodegeneration remain unclear.
Publication · February 01, 2026
Cognitive impairment in chronic migraine compared to pseudotumor cerebri.
Abstract
INTRODUCTION
We aimed to define the prevalence of objective cognitive impairment in a group of chronic migraineurs, and to define how migraineurs with cognitive impairment differed from those without impairment, and in doing so to compa...
Publication · February 01, 2026
Wearable Mechatronic Ultrasound-Integrated AR Navigation System for Lumbar Puncture Guidance
Abstract
As one of the most commonly performed spinal interventions in routine clinical practice, lumbar punctures are usually done with only hand palpation and trial-and-error. Failures can prolong procedure time and introduce complications suc...
Publication · February 01, 2026
Association between basal forebrain and medial temporal lobe tau, and gray matter volume
Abstract
Tau pathology is a hallmark of Alzheimer’s disease (AD). The basal forebrain (BF) is a significant cholinergic projection site with cholinergic groups 1‐3 (Ch1‐3) projecting to the hippocampus, hypothalamus, and olfactory bulb, and grou...
Publication · February 01, 2026
Plasma proteins related to inflammatory diet predict future cognitive impairment
Abstract
Dysregulation of the immune system and dietary patterns that increase inflammation can increase the risk for cognitive decline, but the mechanisms by which inflammatory nutritional habits may affect the development of cognitive impairme...
Publication · February 01, 2026
Exploratory Assessment of Proteomic Network Changes in Cerebrospinal Fluid of Mild Cognitive Impairment Patients: A Pilot Study
Abstract
(1) Background: Despite the existence of well-established, CSF-based biomarkers such as amyloid-β and phosphorylated-tau, the pathways involved in the pathophysiology of Alzheimer’s disease (AD) remain an active area of research. (2) Me...
Publication · February 01, 2026
Decline in proper name retrieval during story recall is associated with Alzheimer’s disease CSF biomarkers in cognitively unimpaired individuals
Abstract
Remembering names of people and places is a common problem in aging that is exacerbated in Alzheimer’s disease (AD). Because retrieval of proper names (PNs) has been associated with brain regions affected by AD (anterior and medial temp...
Publication · February 01, 2026