Research
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Mid-term assessment of transverse sinus stent patency in 104 patients treated for intracranial hypertension secondary to dural sinus stenosis
Abstract
Background Transverse sinus (TS) stenting is a valid treatment alternative for patients with intracranial hypertension caused by underlying bilateral TS stenoses. Its mid-term patency has, however, not been well documented. Objective To...
Publication · February 01, 2026
Effect of Patient-Specific Preanalytic Variables on CSF Aβ1-42 Concentrations Measured on an Automated Chemiluminescent Platform.
Abstract
BACKGROUND
Cerebrospinal fluid (CSF) biomarkers are increasingly used to confirm the accuracy of a clinical diagnosis of mild cognitive impairment or dementia due to Alzheimer disease (AD). Recent evidence suggests that fully automated ...
Publication · February 01, 2026
General Anesthesia Alters Intracranial Venous Pressures during Transverse Sinus Stenting.
Publication · February 01, 2026
CO2 cerebrovascular reactivity measured with phase‐contrast MRI: A potential biomarker of cognition and physical function in older adults
Abstract
Vascular cognitive decline is a prominent cause of late‐life cognitive impairment. Compared to Alzheimer’s disease(AD), there is a paucity of biomarkers for its diagnosis, stratification, and treatment monitoring. Cerebrovascular‐Reacti...
Publication · February 01, 2026
The clinical spectrum of hydrocephalus in adults: report of the first 517 patients of the Adult Hydrocephalus Clinical Research Network registry.
Abstract
OBJECTIVEThe authors describe the demographics and clinical characteristics of the first 517 patients enrolled in the Adult Hydrocephalus Clinical Research Network (AHCRN) during its first 2 years.METHODSAdults ≥ 18 years were nonconsec...
Publication · February 01, 2026
High-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal Patency
Abstract
BACKGROUND AND PURPOSE: Imaging evaluation of ventriculostomy tubes, despite the frequency of malfunction, has remained inadequate due to the absence of a systematic way of assessing the catheter itself. In this retrospective review, we...
Publication · February 01, 2026
A retrospective longitudinal analysis of risk factors, treatment outcomes and imaging parameters of ventricular collapse in idiopathic intracranial hypertension
Abstract
Ventricular collapse is a prevalent yet poorly understood complication of ventriculo-peritoneal shunting (VPS) in idiopathic intracranial hypertension (IIH). By identifying the risk factors of ventricular collapse (VC), this study aims ...
Publication · February 01, 2026
Association of midlife vascular risk and AD biomarkers with subsequent cognitive decline
Abstract
Objective To determine whether vascular risk and Alzheimer disease (AD) biomarkers have independent or synergistic effects on cognitive decline and whether vascular risk is associated with the accumulation of AD pathology as measured by...
Publication · February 01, 2026
Standardized regression-based clinical change score cutoffs for normal pressure hydrocephalus
Abstract
Background Presently, for patients presenting with suspected Normal Pressure Hydrocephalus (NPH) who undergo temporary drainage of cerebrospinal fluid (CSF) there is no defined model to differentiate chance improvement form clinical sig...
Publication · February 01, 2026
Multiplexed Phosphoproteomic Study of Brain in Patients with Alzheimer's Disease and Age-Matched Cognitively Healthy Controls
Abstract
Alzheimer's disease (AD) is the most common neurodegenerative disorder caused by neuronal loss that results in cognitive and functional impairment. Formation of neurofibrillary tangles composed of abnormal hyperphosphorylation of tau pr...
Publication · February 01, 2026
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