Research
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Decoding the circuitry of consciousness: From local microcircuits to brain-scale networks
Abstract
Abstract Identifying the physiological processes underlying the emergence and maintenance of consciousness is one of the most fundamental problems of neuroscience, with implications ranging from fundamental neuroscience to the treatment...
Publication · August 28, 2025
KCNT1 epilepsy with migrating focal seizures shows a temporal sequence with poor outcome, high mortality and SUDEP.
Abstract
Epilepsy of infancy with migrating focal seizures was first described in 1995. Fifteen years later, KCNT1 gene mutations were identified as the major disease-causing gene of this disease. Currently, the data on epilepsy of infancy with ...
Publication · August 28, 2025
Detecting transient brain states of functional connectivity: A comparative study
Abstract
Estimating functional connectivity (FC) has become an increasingly powerful tool for understanding our brain and investigating healthy and abnormal brain functions. Most previous studies assume temporal stationarity, such as correlation...
Publication · August 28, 2025
Dynamics of task-related electrophysiological networks: a benchmarking study
Publication · August 28, 2025
In silico model reveals the key role of GABA in KCNT1‐epilepsy in infancy with migrating focal seizures
Abstract
This study was undertaken to investigate how gain of function (GOF) of slack channel due to a KCNT1 pathogenic variant induces abnormal neuronal cortical network activity and generates specific electroencephalographic (EEG) patterns of ...
Publication · August 28, 2025
An electroencephalography connectome predictive model of major depressive disorder severity
Abstract
Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicti...
Publication · August 28, 2025
Long term evolution of fast ripples during epileptogenesis
Abstract
Objective. Fast ripples (FRs) have received considerable attention in the last decade since they represent an electrophysiological biomarker of the epileptogenic zone (EZ). However, the real dynamics underlying the occurrence, amplitude...
Publication · August 28, 2025
Impaired dynamics of prefrontal beta-band networks during cognitive action control in Parkinson’s disease
Abstract
Among the cognitive symptoms that are associated with Parkinson’s disease (PD), alterations in cognitive action control (CAC) are commonly reported in patients. CAC enables the suppression of an automatic action, in favor of a goal-dire...
Publication · August 28, 2025