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Association between folic acid use during pregnancy and gestational diabetes mellitus: Two population-based Nordic cohort studies
Abstract
Introduction Inconsistent results have been reported on the association between folic acid use in pregnancy and risk of GDM. The aim of this study was to estimate the association between folic acid use and GDM in two population-based No...
Publication · August 21, 2026
MNK2 deficiency potentiates β-cell regeneration via translational regulation
Abstract
Regenerating pancreatic β-cells is a potential curative approach for diabetes. We previously identified the small molecule CID661578 as a potent inducer of β-cell regeneration, but its target and mechanism of action have remained unknow...
Publication · August 21, 2026
Multivalent insulin receptor activation using insulin–DNA origami nanostructures
Abstract
Insulin binds the insulin receptor (IR) and regulates anabolic processes in target tissues. Impaired IR signalling is associated with multiple diseases, including diabetes, cancer and neurodegenerative disorders. IRs have been reported ...
Publication · August 21, 2026
A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration.
Abstract
Building a blastema from the stump is a key step of salamander limb regeneration. Stump-derived cells temporarily suspend their identity as they contribute to the blastema by a process generally referred to as dedifferentiation. Here, w...
Publication · August 21, 2026
Biodistribution of DNA-origami nanostructures in live zebrafish embryos with single-cell resolution
Abstract
DNA origami-based nanotechnology is a versatile tool for exploring fundamental biological questions and holds significant promise for future biomedical applications. However, the development of DNA origami-based therapeutic agents is hi...
Publication · August 21, 2026
Pathways to Adult Sibling Estrangement: Perspectives of Estranged U.S. Adults
Publication · August 21, 2026
Behind the scenes of doctoral success: a mixed methods approach to exploring PhD supervision courses in Swedish higher education institutions
Abstract
ABSTRACT Doctoral education is a critical mission of higher education institutions (HEIs), and supervisors of PhD students have a prominent role in the process. The relevance of their role in a successful PhD experience and outcome rais...
Publication · August 21, 2026
Greasing the machinery toward maturation of stem cell-derived β cells.
Abstract
Getting mature and functional stem cell-derived, insulin-producing β cells is an important step for disease modeling, drug screening, and cell replacement therapy. In this issue, Hua et al.1 used single-cell multiomics analysis coupled ...
Publication · August 21, 2026
Characterization of liver-pancreas crosstalk following β-cell loss reveals a role for the molybdenum cofactor in β-cell regeneration
Abstract
Regeneration of insulin-producing β-cells is an alternative avenue to manage diabetes, and it is crucial to unravel this process in vivo during physiological responses to the lack of β-cells. Here, we aimed to characterize how hepatocyt...
Publication · August 21, 2026
Examining the liver–pancreas crosstalk reveals a role for the molybdenum cofactor in β-cell regeneration
Abstract
Investigation of the inter-organ, pancreas–liver, crosstalk reveals a potential role of the molybdenum biosynthetic pathway in β-cell regeneration. Regeneration of insulin-producing β-cells is an alternative avenue to manage diabetes, a...
Publication · August 21, 2026
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