Research
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Cardiovascular burden in FH families carrying genetic variants affecting LDLR activity
Publication · September 02, 2025
Excess of variants identified in lipid genes as an alternative cause of high LDLC in individuals with FH-phenotype
Publication · September 02, 2025
Rare variants at KCNJ2 are associated with LDL-cholesterol levels in a cross-population study
Publication · September 02, 2025
E_Lipid –Characterisation of the lipid profile of the Portuguese population
Publication · September 02, 2025
Lipids: Emerging Players of Microglial Biology.
Abstract
Lipids are small molecule immunomodulators that play critical roles in maintaining cellular health and function. Microglia, the resident immune cells of the central nervous system, regulate lipid metabolism both in the extracellular env...
Publication · September 02, 2025
One scaffold, different organelle sensors: pH‐activable fluorescent probes for targeting live microglial cell organelles
Abstract
Targeting live cell organelles is essential for imaging, understanding, and controlling specific biochemical processes. Typically, fluorescent probes with distinct structural scaffolds are used to target specific cell organelles. Here, ...
Publication · September 02, 2025
Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time
Abstract
Phagocytosis by glial cells is essential to regulate brain function during development and disease. Given recent interest in using amyloid β (Aβ)-targeted antibodies as a therapy for patients with Alzheimer’s disease, removal of Aβ by p...
Publication · September 02, 2025
Non-uniformly hyperbolic endomorphisms
We show that in nearly every homotopy class of any non-invertible endomorphism of the two-torus there exists a C^1 open set of non-uniformly hyperbolic area preserving maps (one positive and one negative exponent at Lebesgue almost every point), w...
Publication · September 02, 2025
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