Research
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Grasp-Based Functional Coupling Between Reach- and Grasp-Related Components of Forelimb Muscle Activity
Abstract
ABSTRACT How are appropriate combinations of forelimb muscles selected during reach-to-grasp movements in the presence of neuromotor redundancy and important task-related constraints? The authors tested whether grasp type or target loca...
Publication · February 25, 2025
Neuronal Correlates of Functional Coupling between Reach- and Grasp-Related Components of Muscle Activity
Abstract
Coordinated reach-to-grasp movements require precise spatiotemporal synchrony between proximal forelimb muscles (shoulder, elbow) that transport the hand toward a target during reach, and distal muscles (wrist, digit) that simultaneousl...
Publication · February 25, 2025
Impact of Targeted Assistance of Multiarticular Finger Musculotendons on the Coordination of Finger Muscles During Isometric Force Production
Abstract
Neurological injuries often cause degraded motor control. While rehabilitation efforts typically focus on movement kinematics, abnormal muscle activation patterns are often the primary source of impairment. Muscle-based therapies are li...
Publication · February 25, 2025
Inaccurate Use of the Upper Extremity Fugl Meyer Negatively Impacts UE Rehabilitation Trial Design: Findings from the ICARE RCT.
Publication · February 25, 2025
Why Are Stroke Rehabilitation Trial Recruitment Rates in Single Digits?
Abstract
Background: Recruitment of patients in early subacute rehabilitation trials (<30 days post-stroke) presents unique challenges compared to conventional stroke trials recruiting individuals >6 months post-stroke. Preclinical studies sugge...
Publication · February 25, 2025
Shoulder position and handedness differentially affect excitability and intracortical inhibition of hand muscles
Publication · February 25, 2025
Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans
Abstract
Significance Restoration of postinjury brain function is a signal neuroscience challenge. Animal models of stroke recovery demonstrate time-limited windows of heightened motor recovery, similar to developmental neuroplasticity. However,...
Publication · February 25, 2025
Machine Learning Improves Functional Upper Extremity Use Capture in Distal Radius Fracture Patients
Abstract
Summary: Current outcome measures, including strength/range of motion testing, patient-reported outcomes (PROs), and motor skill testing, may provide inadequate granularity in reflecting functional upper extremity (UE) use after distal ...
Publication · February 25, 2025
Interpreting the CPASS Trial: Do Not Shift Motor Therapy to the Subacute Phase
Abstract
The Critical Periods After Stroke Study (CPASS, n = 72) showed that, compared to controls, an additional 20 hours of intensive upper limb therapy led to variable gains on the Action Research Arm Test depending on when therapy was starte...
Publication · February 25, 2025
The Critical Period after Stroke Study (CPASS) Upper Extremity Treatment Protocol
Publication · February 25, 2025
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