Research
Find research shared by the Owlstown community.
Brain Oxygen Extraction by Using MRI in Older Individuals: Relationship to Apolipoprotein E Genotype and Amyloid Burden.
Abstract
Background Apolipoprotein E4 (APOE4) is a major genetic risk factor for late-onset Alzheimer disease. However, the mechanisms by which APOE4 affects the brain, underpinning this risk, have not been fully elucidated. Purpose To investiga...
Publication · February 01, 2026
Quantitative Proteomic Profiling of Cerebrospinal Fluid to Identify Candidate Biomarkers for Alzheimer's Disease
Abstract
The aim of this study is to identify the potential cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease and to evaluate these markers on independent CSF samples using parallel reaction monitoring (PRM) assays.
Publication · February 01, 2026
White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease
Abstract
Objective Recent studies suggest that white matter hyperintensities (WMH) on MRI, which primarily reflect small vessel cerebrovascular disease, may play a role in the evolution of Alzheimer disease (AD). In a longitudinal study, we inve...
Publication · February 01, 2026
Mid-term assessment of transverse sinus stent patency in 104 patients treated for intracranial hypertension secondary to dural sinus stenosis
Abstract
Background Transverse sinus (TS) stenting is a valid treatment alternative for patients with intracranial hypertension caused by underlying bilateral TS stenoses. Its mid-term patency has, however, not been well documented. Objective To...
Publication · February 01, 2026
Effect of Patient-Specific Preanalytic Variables on CSF Aβ1-42 Concentrations Measured on an Automated Chemiluminescent Platform.
Abstract
BACKGROUND
Cerebrospinal fluid (CSF) biomarkers are increasingly used to confirm the accuracy of a clinical diagnosis of mild cognitive impairment or dementia due to Alzheimer disease (AD). Recent evidence suggests that fully automated ...
Publication · February 01, 2026
General Anesthesia Alters Intracranial Venous Pressures during Transverse Sinus Stenting.
Publication · February 01, 2026
CO2 cerebrovascular reactivity measured with phase‐contrast MRI: A potential biomarker of cognition and physical function in older adults
Abstract
Vascular cognitive decline is a prominent cause of late‐life cognitive impairment. Compared to Alzheimer’s disease(AD), there is a paucity of biomarkers for its diagnosis, stratification, and treatment monitoring. Cerebrovascular‐Reacti...
Publication · February 01, 2026
The clinical spectrum of hydrocephalus in adults: report of the first 517 patients of the Adult Hydrocephalus Clinical Research Network registry.
Abstract
OBJECTIVEThe authors describe the demographics and clinical characteristics of the first 517 patients enrolled in the Adult Hydrocephalus Clinical Research Network (AHCRN) during its first 2 years.METHODSAdults ≥ 18 years were nonconsec...
Publication · February 01, 2026
High-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal Patency
Abstract
BACKGROUND AND PURPOSE: Imaging evaluation of ventriculostomy tubes, despite the frequency of malfunction, has remained inadequate due to the absence of a systematic way of assessing the catheter itself. In this retrospective review, we...
Publication · February 01, 2026
Sites
View all
Create your academic website in Owlstown
Start your academic website in just a few minutes. Keep it updated easily. No code, no server to maintain, so you can focus on your research.
Create your free website