Research
Find research shared by the Owlstown community.
Pathophysiology of ion channels in amyotrophic lateral sclerosis
Abstract
Amyotrophic lateral sclerosis (ALS) stands as the most prevalent and severe form of motor neuron disease, affecting an estimated 2 in 100,000 individuals worldwide. It is characterized by the progressive loss of cortical, brainstem, and...
Publication · February 17, 2026
Homocysteine enhances the excitability of cultured hippocampal neurons without altering the gene expression of voltage-gated ion channels
Abstract
Elevated plasma homocysteine (Hcy) levels lead to hyperhomocysteinemia, a condition associated with various neurological disorders affecting multiple brain regions, including the hippocampus. In this study, we investigated the effects o...
Publication · February 17, 2026
Functional characterization of a novel de novo CACNA1C pathogenic variant in a patient with neurodevelopmental disorder
Abstract
Mutations in CACNA1C, the gene encoding Cav1.2 voltage-gated calcium channels, are associated with a spectrum of disorders, including Timothy syndrome and other neurodevelopmental and cardiac conditions. In this study, we report a child...
Publication · February 17, 2026
Young people’s perspectives on the world around them and contexts of digital citizenship
Publication · February 17, 2026
Hatedom multiplataforma: Estrategias de los influencers para gestionar la aversión afectiva
Publication · February 17, 2026
The timing of antenatal glucocorticoids determines the receptor sensitivity in preterm infants
Publication · February 17, 2026
Natural Disasters, Consumption and Climate Change Nexus: The Role of Green Technologies
Publication · February 17, 2026
Open-Source Low-cost Melt Flow Indexer
Overview
This open-source material-testing tool, a Melt Flow Index (MFI) tester, provides an accessible and cost-effective system for evaluating melt-flow behavior of polymer-based feedstocks intended for additive-manufacturing processes. Its ...
Project · February 17, 2026
Parametric R&D Thermal Battery Module
Overview
This open-source parametric CAD definition enables customizable 3D-printable thermal battery modules for accessible and cost-effective testing in the R&D and laboratory settings and evaluation of thermal energy for sustainable applica...
Project · February 17, 2026
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