Research
Find research shared by the Owlstown community.
Development of new non-opioid calcium channel antagonists for pain management
It is estimated that chronic pain affects at least 10% of the world’s population and is one of the main reasons adults seek medical attention, causing a huge burden on families and society. Although the main therapeutics for the treatment of pain ...
Project · February 18, 2026
Unraveling the regulatory landscape of neuronal T-type calcium channel variants in human disease
T-type calcium channels play a vital role in neuronal excitability, hormone secretion, and development. Genetic variations in these channels are associated with disorders such as epilepsy, autism spectrum disorders, and schizophrenia. However, cur...
Project · February 18, 2026
Design for replicability in open-source distributed assistive technology for low-resource settings: a case study of two-piece 3D-printed forearm crutches
Abstract
Purpose: Distributed manufacturing of open-source assistive technology shows potential to offer accessible, affordable, and customizable solutions for users in low-resource contexts. Their real-world adoption, however, depends not only ...
Publication · February 18, 2026
Mechanical static loading testing rig for forearm crutches
Overview
This open-source testing rig allows for easy, replicable static loading testing setup for mobility aid, in this case, forearm crutches. Its configuration replicates realistic biomedical loading conditions during device use, thanks to ...
Project · February 18, 2026
[J26] On the application of the Nyström method to two-dimensional neutral particle transport problems in heterogeneous media
ABSTRACT: Over time, several methods were developed to deal with neutral particle transport problems. The interest in these problems is related to their wide range of applications, from neutron transport and heat transfer in nuclear reactors to r...
Publication · February 17, 2026
The Effectiveness of Digital Interventions for Enhancing Empathy in Adults: A Meta-Analysis of Randomized Controlled Trials
Publication · February 17, 2026
Complex and Messy Prebiotic Chemistry: Obstacles and Opportunities for an RNA World
Abstract
Traditional prebiotic chemistry experiments often isolated single reactions under clean, controlled conditions, yet early Earth was chemically diverse and physically dynamic. Such primordial complexity likely imposed obstacles, includin...
Publication · February 17, 2026
Role of astrocytes of the master circadian pacemaker in the integration of time cues (StarTime)
This project seeks to redefine how the mammalian circadian system operates. The suprachiasmatic nucleus (SCN), the brain’s master clock, coordinates daily physiology by receiving light input and synchronizing time signals throughout the body. Trad...
Project · February 17, 2026
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