Research
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Location matters: defining the architecture of the bronchial wall in health and asthma
Publication · May 20, 2026
Epithelial cell-derived lumican modulates extracellular matrix dynamics in early-life airways disease.
Abstract
BACKGROUND
Airway remodelling is a prominent pathological feature in pre-school wheeze (PSW) and school-age asthma (SA). Although the relationships between altered lung function, extracellular matrix (ECM) changes and airway remodelling...
Publication · May 20, 2026
Mast Cells Promote Inflammatory Th17 Cells and Impair Treg Cells Through an IL-1β and PGE2 Axis
Abstract
Purpose CD4+ effector T cells (Teffs) play a key role in immune responses by infiltrating the sites of inflammation and modulating local leukocyte activity. In turn resident immune cells shape their response. This study aimed to investi...
Publication · May 20, 2026
Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge
Abstract
Respiratory infections that result in severe and life-threatening immune-mediated respiratory decline are a major public health issue. Controlling local respiratory immune reactions without the use of systemic immunosuppressants remain...
Publication · May 20, 2026
Redefining airway wall immune–epithelial interactions using single-cell spatial transcriptomics
Publication · May 20, 2026
Adaptable Pectin Extraction and Functional Group Impact on Electrolytes Suitable for Energy Storage Applications
An alkaline de-esterification method was developed to modify the functional properties of pectin extracted from soybean hull waste. The process yielded pectin with degrees of esterification (DE) ranging from 40 to 0.40, which was then incorporated...
Publication · May 20, 2026
3D Tumor-Mimicking Phantom Models for Assessing NIR I/II Nanoparticles in Fluorescence-Guided Surgical Interventions
Fluorescence image-guided surgery (FIGS) offers high spatial resolution and real-time feedback but is limited by shallow tissue penetration and autofluorescence from current clinically approved fluorophores. The near-infrared (NIR) spectrum, speci...
Publication · May 20, 2026
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