Research
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Tumor PD-L1 expression and Nivolumab efficacy: meta-analysis of phase III randomized clinical trials
Abstract
Introduction and aims
Nivolumab is a monoclonal antibody that binds to the PD-1 receptor expressed by activated T-cells activating thus an immune response against tumor cells. We conducted a meta-analysis to investigate the effect of tumo...
Publication · January 05, 2026
Tumor PD-L1 expression and Nivolumab efficacy in the treatment of cancer: a meta-analysis of phase III randomized clinical trials
Abstract
Introduction and aims:
Nivolumab is a fully-humanized IgG4 monoclonal antibody that binds to the PD-1 receptor expressed by activated T-cells blocking thus the immune checkpoint and activating an immune response to tumor cells [1]. We con...
Publication · January 05, 2026
Basal ganglia dynamics in parkinsonism and persistent motor rescue
Current trainees: Anna Thomas (Pitt Mathematics), Emma Gao (Gittis lab at CMU)
Overarching questions: How do basal ganglia outputs change in parkinsonism? How can the altered dynamics be modulated to (persistently) improve motor function?
Som...
Project · January 04, 2026
Decision dynamics in cortico-basal ganglia-thalamic networks
Current trainees: Zhuojun Yu (CMU), Cristina Giossi & Alex G. O'Hare (UIB), Kayla Kraeuter (Pitt)
Overarching questions: How do the basal ganglia interact with cortical and thalamic neurons to influence our decision-making, action selection, a...
Project · January 04, 2026
Indonesian Science Communication Lab (IDSCL)
The Indonesian Science Communication Lab (IDSCL) was established in 2023 with the initiative built on the awareness that a collaborative networking platform was needed for researchers, science communicators, journalists, and the science-interested...
Project · January 04, 2026
Role-Conditioned Refusals: Evaluating Access Control Reasoning in Large Language Models
Publication · January 03, 2026
Roots and effects of sexual harassment
Overview
This project examines sexual harassment from multiple angles, integrating diverse research methods to explore its sociopsychological roots and broad impacts on individuals and society. By combining quantitative surveys and qualitative an...
Project · January 03, 2026
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