Research
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Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease?
Abstract
In general terms we all use the word “stress” to describe our discomfort in coping with challenges of daily life. This is mostly related to our subjective perceptions of workload and/or other unexpected physical or mental efforts we are...
Publication · August 10, 2026
Hypertensive crisis in pregnancy due to a metamorphosing pheochromocytoma with postdelivery Cushing's syndrome
Publication · August 10, 2026
Expression of progenitor markers is associated with the functionality of a bioartificial adrenal cortex
Abstract
Encapsulation of primary bovine adrenocortical cells in alginate is an efficacious model of a bioartificial adrenal cortex. Such a bioartificial adrenal cortex can be used for the restoration of lost adrenal function in vivo as well as ...
Publication · August 10, 2026
Adrenal cortex–medulla interactions in adaptation to stress and disease
Abstract
Abstract The adrenal gland plays a major role in response to physiological challenges and is able to adapt to homeostatic alterations. The adrenal is composed of two different tissue types in a bidirectional connection, the medulla, and...
Publication · August 10, 2026
The adrenal gland in stress - Adaptation on a cellular level.
Abstract
Human individuals are constantly confronted to various kinds of stressors and the body's response and adaptation is essential for human health. The adrenal gland as the main producer of stress hormones plays a major role in the response...
Publication · August 10, 2026
Insulin and obesity transform hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state
Abstract
Objective Metabolic diseases are an increasing problem in society with the brain-metabolic axis as a master regulator of the human body for sustaining homeostasis under metabolic stress. However, metabolic inflammation and disease will ...
Publication · August 10, 2026
New Horizons: Novel Adrenal Regenerative Therapies
Abstract
Abstract Adrenal insufficiency requires lifelong corticoid replacement therapies. However, current therapies are not able to replace the physiological circadian pattern of the adrenal cortex and are associated with many metabolic, vascu...
Publication · August 10, 2026
Are Nestin-positive cells responsive to stress?
Abstract
Abstract In a number of adult tissues, Nestin-positive stem cells/progenitors have been identified and shown to be involved in maintenance and remodeling. Various studies have shown that under stressful conditions, quiescent Nestin-posi...
Publication · August 10, 2026
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), fi rst identi fi ed in December 2019, causes coronavirus disease 2019 (COVID-19). It is reasonable to presume that SARS-CoV-2 infection will cause activation of the endocrine s...
Publication · August 10, 2026
The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease
Abstract
Abstract Currently, we are experiencing a true pandemic of a communicable disease by the virus SARS-CoV-2 holding the whole world firmly in its grasp. Amazingly and unfortunately, this virus uses a metabolic and endocrine pathway via AC...
Publication · August 10, 2026
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