Laboratory for Genomics and Genetic Therapies
Led by Phillip A. Doerfler, Ph.D.
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Description
You can visit the academic website of Laboratory for Genomics and Genetic Therapies (Led by Phillip A. Doerfler, Ph.D.) at https://doerflerlab.research.st.
Recent Updates
Systematic benchmarking of CUT&Tag improves the reliability and reproducibility of chromatin analysis
Publication
Abstract Cleavage under target and tagmentation (CUT&Tag) is a widely used method for profiling chromatin occupancy; however, its repro...
Single-cell transcriptomics reveals heterocellular γ-globin gene expression in Aγδβ-thalassemia
Publication
Removal of promoter CpG methylation by epigenome editing reverses HBG silencing
Publication
Abstract β-hemoglobinopathies caused by mutations in adult-expressed HBB can be treated by re-activating the adjacent paralogous genes ...