Research
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Alzheimer’s and neurodegenerative disease biomarkers in blood predict brain atrophy and cognitive decline
Abstract
Background Although blood-based biomarkers have been identified as cost-effective and scalable alternatives to PET and CSF markers of neurodegenerative disease, little is known about how these biomarkers predict future brain atrophy and...
Publication · February 01, 2026
Preoperative neurofilament light associated with postoperative delirium in hip fracture repair patients without dementia.
Publication · February 01, 2026
MRI-Based Prediction of Clinical Improvement after Ventricular Shunt Placement for Normal Pressure Hydrocephalus: Development and Evaluation of an Integrated Multisequence Machine Learning Algorithm
Abstract
BACKGROUND AND PURPOSE: Symptoms of normal pressure hydrocephalus (NPH) are sometimes refractory to shunt placement, with limited ability to predict improvement for individual patients. We evaluated an MRI-based artificial intelligence ...
Publication · February 01, 2026
Proteomic analyses reveal plasma EFEMP1 and CXCL12 as biomarkers and determinants of neurodegeneration
Abstract
Plasma proteomic analyses of unique brain atrophy patterns may illuminate peripheral drivers of neurodegeneration and identify novel biomarkers for predicting clinically relevant outcomes.
Publication · February 01, 2026
Diagnostic and Prognostic Biomarkers of Idiopathic Normal Pressure Hydrocephalus in Cerebrospinal Fluid and Blood.
Publication · February 01, 2026
Clinical Features and Diagnosis of Normal Pressure Hydrocephalus
Abstract
ABSTRACT OBJECTIVE This article serves as a practical guide for the assessment of patients with suspected idiopathic normal pressure hydrocephalus (NPH). LATEST DEVELOPMENTS Significant advancements in neuroimaging, biomarker identifica...
Publication · February 01, 2026
The contribution of lumbar puncture opening pressure in the diagnosis of spontaneous intracranial hypotension: A systematic literature review and meta-analysis.
Abstract
OBJECTIVE
The objective of this study was to summarize the available evidence regarding the clinical value and trend over time of lumbar cerebrospinal fluid (CSF) opening pressure utilization to diagnose spontaneous intracranial hypoten...
Publication · February 01, 2026
Prestige or Pretense? Insiders’ Perspectives on the Canada 150 Chair Program
Publication · February 01, 2026
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