Research
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THE CONTRIBUTION OF SEX-SPECIFIC ASSOCIATIONS IN GENETIC STUDIES OF ALZHEIMER’S DISEASE PATHOLOGY
Publication · February 01, 2026
Does the Presence or Absence of DESH Predict Outcomes in Adult Hydrocephalus?
Abstract
BACKGROUND AND PURPOSE: The DESH (disproportionately enlarged subarachnoid-space hydrocephalus) pattern of “tight high-convexity and medial subarachnoid spaces, and enlarged Sylvian fissures with ventriculomegaly” is used to determine w...
Publication · February 01, 2026
Single-Element Needle-Based Ultrasound Imaging of the Spine: An In Vivo Feasibility Study
Publication · February 01, 2026
Characterization of 3 Novel Tau Radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in Healthy Controls and in Alzheimer Subjects
Abstract
11C-RO-963, 11C-RO-643, and 18F-RO-948 (previously referred to as 11C-RO6924963, 11C-RO6931643, and 18F-RO6958948, respectively) have been reported as promising PET tracers for tau imaging based on in vitro and preclinical PET data. Her...
Publication · February 01, 2026
Non‐contrast MR imaging of blood‐brain barrier permeability to water
Publication · February 01, 2026
Identifying Changepoints in Biomarkers During the Preclinical Phase of AD
Abstract
Objective Several models have been proposed for the evolution of Alzheimer’s disease (AD) biomarkers. The aim of this study was to identify changepoints in a range of biomarkers during the preclinical phase of AD. Methods We examined ni...
Publication · February 01, 2026
Phosphotyrosine profiling of human cerebrospinal fluid
Abstract
Cerebrospinal fluid (CSF) is an important source of potential biomarkers that affect the brain. Biomarkers for neurodegenerative disorders are needed to assist in diagnosis, monitoring disease progression and evaluating efficacy of ther...
Publication · February 01, 2026
Comparing Shunt Survival of Adult Hydrocephalus: An Analysis of Shunt Failure Using the National Longitudinal Database
Publication · February 01, 2026
ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes
Abstract
Objective To examine the long-term cognitive trajectories of individuals with normal cognition at baseline and distinct amyloid/tau/neurodegeneration (ATN) profiles. Methods Pooling data across 4 cohort studies, 814 cognitively normal p...
Publication · February 01, 2026
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