Research
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Adjusting Machine Learning Decisions for Equal Opportunity and Counterfactual Fairness
Abstract
Machine learning ( ml ) methods have the potential to automate high-stakes decisions, such as bail admissions or credit lending, by analyzing and learning from historical data. But these algorithmic decisions may be unfair: in learning ...
Publication · 8h
Sparsity regularization via tree-structured environments for disentangled representations
Abstract
Many causal systems such as biological processes in cells can only be observed indirectly via measurements, such as gene expression. Causal representation learning -- the task of correctly mapping low-level observations to latent causal...
Publication · 8h
Dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke in middle aged male and female mice
Abstract
Nutrition is a modifiable risk factor for ischemic stroke. As people age their ability to absorb some nutrients decreases, a primary example is vitamin B12. Older individuals with a vitamin B12 deficiency are at a higher risk for ischem...
Publication · 10h
Ischemic Stroke and Dietary Vitamin B12 Deficiency in Old-Aged Females: Impaired Motor Function, Increased Ischemic Damage Size, and Changed Metabolite Profiles in Brain and Cecum Tissue
Abstract
The global population is aging and the prevalence of age-related diseases, such as stroke, is predicted to increase. A vitamin B12 deficiency (vit. B12 def.) is common in the elderly, because of changes in metabolism. Clinical studies h...
Publication · 10h
The impact of maternal dietary folic acid or choline deficiencies on cerebral blood flow, cardiac, aortic, and coronary function in young and middle-aged female mouse offspring following ischemic stroke
Abstract
Background and Purpose Adequate maternal dietary levels of one-carbon (1C) metabolites, such as folic acid and choline, play an important role in the closure of the neural tube in utero; however, the impact of deficiencies in 1C on offs...
Publication · 10h
The U.S. faculty job market survives the SARS-CoV-2 global pandemic
Abstract
Purpose This paper aims to identify the extent to which the COVID-19 pandemic disrupted the academic job market and the ways in which faculty job applicants altered their applications in response to a changing academia. Design/methodolo...
Publication · 10h
Maternal dietary deficiencies in folic acid or choline reduce primary neuron viability after exposure to hypoxia through increased levels of apoptosis
Abstract
Stoke is the leading cause of death and disability globally. By addressing modifiable risk factors, particularly nutrition, the prevalence of stroke and its dire consequences can be mitigated. One-carbon (1C) metabolism is a critical bi...
Publication · 10h
Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke
Abstract
Ischemic stroke is a debilitating disease, with nutrition being a modifiable risk factor. Changes in levels of metabolites can be used to measure the alterations in the gut, a significant marker for the etiology of diseases. This study ...
Publication · 10h
An updated and expanded characterization of the biological sciences academic job market
Abstract
In the biological sciences, many areas of uncertainty exist regarding the factors that contribute to success within the faculty job market. Earlier work from our group reported that beyond certain thresholds, academic and career metrics...
Publication · 10h
Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice
Abstract
Ischemic stroke is one of the leading causes of disability and death globally, with a rising incidence in younger age groups. It’s well known that maternal diet during pregnancy and lactation is vital for the early neurodevelopment of o...
Publication · 10h