Research
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Protocol for a randomized controlled trial examining multilevel prediction of response to behavioral activation and exposure-based therapy for generalized anxiety disorder
Abstract
BackgroundOnly 40–60% of patients with generalized anxiety disorder experience long-lasting improvement with gold standard psychosocial interventions. Identifying neurobehavioral factors that predict treatment success might provide spec...
Publication · August 25, 2025
Behavioral activation therapy for depression is associated with a reduction in the concentration of circulating quinolinic acid
Abstract
Abstract Background An inflammation-induced imbalance in the kynurenine pathway (KP) has been reported in major depressive disorder but the utility of these metabolites as predictive or therapeutic biomarkers of behavioral activation (B...
Publication · August 25, 2025
The Impact of COVID-19 on Adolescent Mental Health: Preliminary Findings From a Longitudinal Sample of Healthy and At-Risk Adolescents
Abstract
Background: The COVID-19 pandemic has brought on far-reaching consequences for adolescents. Adolescents with early life stress (ELS) may be at particular risk. We sought to examine how COVID-19 impacted psychological functioning in a sa...
Publication · August 25, 2025
I’m still standing: A machine learning analysis of risk and protective factors of suicidal thoughts and behaviors in college students
Abstract
Background: An estimated 1100 college students die by suicide each year. Our ability to predict who is at risk for suicide, as well as our knowledge of resilience factors protecting against it, remains limited. We used a machine learnin...
Publication · August 25, 2025
Extracurricular activities, screen media activity, and sleep may be modifiable factors influencing children’s cognitive functioning: Evidence from the ABCD study
Abstract
PurposeFluid cognitive functioning (FCF), or the capacity to learn, solve problems, and adapt to novel situations, is instrumental for academic success, psychological well-being, and adoption of healthy behaviors. Our knowledge concerni...
Publication · August 25, 2025
A pragmatic clinical trial examining the impact of a resilience program on college student mental health
Abstract
One in three college students experience significant depression or anxiety interfering with daily functioning. Resilience programs that can be administered to all students offer an opportunity for addressing this public health problem. ...
Publication · August 25, 2025
The effect of mindfulness-based stress intervention on neurobiological and symptom measures in adolescents with early life stress: A feasibility randomized controlled trial
Abstract
Background Early life stress (ELS) has been linked to poor mental and physical health outcomes in adolescence and adulthood. Mindfulness reduces symptoms of depression and anxiety and improves cognitive and social outcomes in both youth...
Publication · August 25, 2025
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