Blog Posts
Find blog posts shared by the Owlstown community.
A cell eating itself, leveraging autophagy to treat cancer
What is autophagy?
Autophagy is a process by which the cell can maintain and recycle its components. The process starts by forming a membrane around the target. This structure then is fused with lysosomes which contain enzymes to lyse and degrad...
Post · January 09, 2023
Cancer evolution by non-Darwinian mechanisms
In the Darwinian model of cancer evolution, the variations among cancer cells result in differential survival of some clones, which dominate the tumor mass. This view was challenged by discovering that tumors comprised multiple subclones that diff...
Post · January 09, 2023
The evolution of self-consumption
To study the evolution of a body part or a trait, one needs to address two questions. First, what is the trait for? Second, how could it evolve in small steps that gave some advantage to the organism that carried them? It is also necessary to sugg...
Post · January 09, 2023
The non-genetic determinants in cancer evolution
When one lines up the genomes of related species, they vary in more than the protein-coding sequences. In fact, most differences fall outside these regions, given the small fraction they represent. Genomes differ with respect to sequences that reg...
Post · January 09, 2023
Gene expression adaptation in yeast, mice, and humans
Coding vs. non-coding variants
Mutations produce novelty. The kind of novel variants on which selection acts. These variants fall within two broad categories depending on location in the genome: protein-coding and regulatory sequences. The forme...
Post · January 09, 2023
The evolutionary war — how to beat cancer in its own game
Cancer evolves. That much is known and agreed upon. Researchers still, however, debate the detailed picture of how cancer came to be and why it still plages our species is subject to debate. Studying cancer through an evolutionary lens could provi...
Post · January 09, 2023
Public data for the public good
The human genome project galvanized the scientific community around an ambitious goal. It produced several crucial discoveries, and a new era of research began. For the first time, it became possible to estimate the number of human genes and compi...
Post · January 09, 2023
Celebrity Endorsements & Crypto
Has the FTX collapse undermined the usefulness of celebrity endorsements?
FTX hired major celebrities, such as Tom Brady, Stephen Curry, Larry David, and Gisele Bundchen, who were featured in Super Bowl commercials and national magazine ads, but...
Post · January 08, 2023
PSMR-TBP 2022 9th Conference on PET/MR and SPECT/MR & Total-body PET workshop, 28 May - 1 June 2022, La Biodola, Isola d'Elba, Italy
Leo, Thomas, and Dr. Schweser had the pleasure of attending the 2022 PET, SPECT and MR Total Body PET (PSMR-TBP) Conference in Isola d'Elba, Italy. This conference provided an opportunity to present and discuss their research and learn about the l...
Post · December 28, 2022
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